Varaico: Literature-Extracted Genetic Variants

Gene:SPOP
Variant:p.E47A
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SPOP

NM_001007228.2:p.E47A

Associated Papers

The equilibrium between two quaternary assembly states determines the activity of SPOP and its cancer mutants.

Cuneo MJ et al.

Biorxiv : the Preprint Server for Biology, 2025

Pervasive mislocalization of pathogenic coding variants underlying human disorders.

Lacoste J et al.

Cell, 2024

Pervasive mislocalization of pathogenic coding variants underlying human disorders.

Lacoste J et al.

Biorxiv : the Preprint Server for Biology, 2023

Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.

Janouskova H et al.

Nature Medicine, 2017

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