Varaico: Literature-Extracted Genetic Variants

Gene:SPP1
Variant:p.A22A
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SPP1

NM_001040058.2:p.A22A

Associated Papers

Biomarkers in Duchenne Muscular Dystrophy: Current Status and Future Directions.

Fortunato F et al.

Journal of Neuromuscular Diseases, 2023

The Role of Single-Nucleotide Polymorphisms in Cholangiocarcinoma: A Systematic Review.

Wang G et al.

Cancers, 2022

Genetic modifiers and phenotypic variability in neuromuscular disorders.

Mroczek M et al.

Journal of Applied Genetics, 2020

Genetics of Degenerative Cervical Myelopathy: A Systematic Review and Meta-Analysis of Candidate Gene Studies.

Pope DH et al.

Journal of Clinical Medicine, 2020

Genetic Modifiers of Duchenne Muscular Dystrophy in Chinese Patients.

Chen M et al.

Frontiers in Neurology, 2020

Genetic factors of cervical spondylotic myelopathy-a systemic review.

Wang G et al.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 2017

Osteopontin splice variants and polymorphisms in cancer progression and prognosis.

Briones-Orta MA et al.

Biochimica Et Biophysica Acta. Reviews on Cancer, 2017

Osteopontin, Bone Morphogenetic Protein-4, and Vitamin D Receptor Gene Polymorphisms in the Susceptibility and Clinical Severity of Spinal Tuberculosis.

Wang G et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2017

Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing.

Baumert P et al.

European Journal of Applied Physiology, 2016

Secreted Phosphoprotein 1 Promoter Genetic Variants Are Associated with the Response to Pegylated Interferon α Plus Ribavirin Combination Therapy in Egyptian Patients with Chronic Hepatitis C Virus Infection.

Ali FT et al.

Gut and Liver, 2015

Association of SPP1 promoter variants with hip osteoarthritis susceptibility in Chinese population.

Lv C et al.

Gene, 2015

The OPN gene polymorphism confers the susceptibility and response to Ara-C based chemotherapy in Chinese AML patients.

Zhang R et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2015

Associations between the Genetic Polymorphisms of Osteopontin Promoter and Susceptibility to Cancer in Chinese Population: A Meta-Analysis.

Liu Y et al.

Plos One, 2015

Milder course in Duchenne patients with nonsense mutations and no muscle dystrophin.

Zatz M et al.

Neuromuscular Disorders : Nmd, 2014

Eccentric muscle challenge shows osteopontin polymorphism modulation of muscle damage.

Barfield WL et al.

Human Molecular Genetics, 2014

Serum osteopontin, but not OPN gene polymorphism, is associated with LVH in essential hypertensive patients.

Hou X et al.

Journal of Molecular Medicine (berlin, Germany), 2014

OPN polymorphism is associated with the susceptibility to cervical spondylotic myelopathy and its outcome after anterior cervical corpectomy and fusion.

Wu J et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2014

OPN Polymorphism Is Related to the Chemotherapy Response and Prognosis in Advanced NSCLC.

Hao Y et al.

International Journal of Genomics, 2014

Polymorphism -433 C>T of the Osteopontin gene is associated with the susceptibility to develop gliomas and their prognosis in a Chinese cohort.

Shen Z et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2014

Association between polymorphisms in osteopontin gene (SPP1) and first episode calcium oxalate urolithiasis.

Safarinejad MR et al.

Urolithiasis, 2013

Osteopontin promoter polymorphisms are associated with susceptibility to gastric cancer.

Lee TY et al.

Journal of Clinical Gastroenterology, 2013

OPN gene polymorphism (Ala250) and lower serum OPN levels are associated with urolithiasis.

Tugcu V et al.

Renal Failure, 2013

OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population.

Jiang Y et al.

Arthritis Research & Therapy, 2013

OPN -443C>T genetic polymorphism and tumor OPN expression are associated with the risk and clinical features of papillary thyroid cancer in a Chinese cohort.

Mu G et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2013

OPN gene polymorphism and the serum OPN levels confer the susceptibility and prognosis of ischemic stroke in Chinese patients.

Jing M et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2013

Importance of SPP1 genotype as a covariate in clinical trials in Duchenne muscular dystrophy.

Bello L et al.

Neurology, 2012

Performance of an adipokine pathway-based multilocus genetic risk score for prostate cancer risk prediction.

Ribeiro RJ et al.

Plos One, 2012

The impact of osteopontin gene variations on multiple sclerosis development and progression.

Comi C et al.

Clinical & Developmental Immunology, 2012

Association between osteopontin promoter variants and diastolic dysfunction in hypertensive heart in the Japanese population.

Nakayama H et al.

Hypertension Research : Official Journal of the Japanese Society of Hypertension, 2011

OPN gene polymorphisms are associated with susceptibility and clinicopatholigical characteristics of cervical cancer in a Chinese cohort.

Xu Q et al.

Cancer Biomarkers : Section a of Disease Markers, 2011

SPP1 promoter polymorphisms and glioma risk in a Chinese Han population.

Chen J et al.

Journal of Human Genetics, 2010

The impact of osteopontin promoter polymorphisms on the risk of calcium urolithiasis.

Liu CC et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2010

The implication of osteopontin (OPN) expression and genetic polymorphisms of OPN promoter in oral carcinogenesis.

Chiu YW et al.

Oral Oncology, 2010

Osteopontin: an early innate immune marker of Escherichia coli mastitis harbors genetic polymorphisms with possible links with resistance to mastitis.

Alain K et al.

Bmc Genomics, 2009

Association of alleles at polymorphic sites in the Osteopontin encoding gene in young type 1 diabetic patients.

Marciano R et al.

Clinical Immunology (orlando, Fla.), 2009

Osteopontin promoter polymorphism is associated with increased carotid intima-media thickness.

de las Fuentes L et al.

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography, 2008

SPP1 promoter polymorphisms: identification of the first modifier gene for pseudoxanthoma elasticum.

Hendig D et al.

Clinical Chemistry, 2007

A functional polymorphism in the Eta-1 promoter is associated with allele specific binding to the transcription factor Sp1 and elevated gene expression.

Hummelshoj T et al.

Molecular Immunology, 2006

Two single-nucleotide polymorphisms in the 5' and 3' ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus.

D'Alfonso S et al.

Arthritis and Rheumatism, 2005

Polymorphisms in the osteopontin promoter affect its transcriptional activity.

Giacopelli F et al.

Physiological Genomics, 2004

The osteopontin gene +1239A/C single nucleotide polymorphism is associated with type 1 diabetes mellitus in the Italian population.

Chiocchetti A et al.

International Journal of Immunopathology and Pharmacology, 0

Genetic Modifiers for Neuromuscular Diseases.

Lamar KM et al.

Journal of Neuromuscular Diseases, 0

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