Varaico: Literature-Extracted Genetic Variants

Gene:SPPL2B
Variant:p.G420A
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SPPL2B

NM_152988.3:p.G420A

Associated Papers

Three-amino acid spacing of presenilin endoproteolysis suggests a general stepwise cleavage of gamma-secretase-mediated intramembrane proteolysis.

Fukumori A et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2010

Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.

Fluhrer R et al.

The Journal of Biological Chemistry, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."