Associated Papers
In vitro cleavage of tumor necrosis factor α (TNFα) by Signal-Peptide-Peptidase-like 2b (SPPL2b) resembles mechanistic principles observed in the cellular context.
Sharrouf K et al.
Chemico-biological Interactions, 2024
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
Mentrup T et al.
The Journal of Experimental Medicine, 2019
CLN5 is cleaved by members of the SPP/SPPL family to produce a mature soluble protein.
Jules F et al.
Experimental Cell Research, 2017
Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
Fleck D et al.
The Journal of Biological Chemistry, 2016
Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.
Fluhrer R et al.
The Journal of Biological Chemistry, 2008
Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
Martin L et al.
The Journal of Biological Chemistry, 2008
Select a paper to view details