Associated Papers
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability.
Dürauer S et al.
Nature Communications, 2025
Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes.
Saha LK et al.
Nature Communications, 2023
37024461 (PubMed )
Supplement: 41467_2023_37498_MOESM2_ESM.pdf
SPRTN patient variants cause global-genome DNA-protein crosslink repair defects.
Weickert P et al.
Nature Communications, 2023
Mechanisms and Regulation of DNA-Protein Crosslink Repair During DNA Replication by SPRTN Protease.
Perry M et al.
Frontiers in Molecular Biosciences, 2022
Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Li F et al.
Cell Reports, 2019
Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.
Stingele J et al.
Molecular Cell, 2016
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