Varaico: Literature-Extracted Genetic Variants

Gene:SQSTM1
Variant:p.E352A
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SQSTM1

NM_003900.5:p.E352A

Associated Papers

Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease.

Mercado N et al.

Faseb Bioadvances, 2019

Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin.

Jin YN et al.

Plos One, 2013

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.

Jain A et al.

The Journal of Biological Chemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."