Associated Papers
Genetic and clinical landscape of Chinese frontotemporal dementia: dominance of TBK1 and OPTN mutations.
Nan H et al.
Alzheimer's Research & Therapy, 2024
Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
Cazzaro S et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023
Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.
Ikeda R et al.
The Embo Journal, 2023
Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation.
Liu H et al.
Scientific Reports, 2021
SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation.
Fang C et al.
Autophagy, 2021
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Lee S et al.
Autophagy, 2020
Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress.
Peng H et al.
Cell Research, 2017
ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress.
Lee H et al.
Molecular Neurobiology, 2016
Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy.
Park S et al.
Plos One, 2016
p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium.
Wang L et al.
Biochimica Et Biophysica Acta, 2014
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