Varaico: Literature-Extracted Genetic Variants

Gene:SQSTM1
Variant:p.E409K
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SQSTM1

NM_003900.5:p.E409K

Associated Papers

Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination.

Lee Y et al.

Cell Reports, 2017

Impact of p62/SQSTM1 UBA domain mutations linked to Paget's disease of bone on ubiquitin recognition.

Garner TP et al.

Biochemistry, 2011

Dimerisation of the UBA domain of p62 inhibits ubiquitin binding and regulates NF-kappaB signalling.

Long J et al.

Journal of Molecular Biology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."