Varaico: Literature-Extracted Genetic Variants

Gene:SRC
Variant:p.T341M
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SRC

NM_198291.3:p.T341M

Associated Papers

The Mitogen-Activated Protein Kinase Pathway Facilitates Resistance to the Src Inhibitor Dasatinib in Thyroid Cancer.

Beadnell TC et al.

Molecular Cancer Therapeutics, 2016

Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer.

Terai H et al.

Acs Chemical Biology, 2015

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.

Dale T et al.

Nature Chemical Biology, 2015

26502155 (PubMed )
Supplement: NIHMS65392-supplement-SuppInfo.pdf

Activation of tyrosine kinases by mutation of the gatekeeper threonine.

Azam M et al.

Nature Structural & Molecular Biology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."