Varaico: Literature-Extracted Genetic Variants

Gene:SRC
Variant:p.Y530F
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SRC

NM_198291.3:p.Y530F

Associated Papers

Twinfilin-1 phosphorylation in reelin signaling regulates actin dynamics and spine development.

Dong G et al.

Pharmacological Research, 2025

An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function.

Cuesta-Hernández HN et al.

Nature Communications, 2023

FNDC5/irisin facilitates muscle-adipose-bone connectivity through ubiquitination-dependent activation of runt-related transcriptional factors RUNX1/2.

He X et al.

The Journal of Biological Chemistry, 2022

Mutant TP53 interacts with BCAR1 to contribute to cancer cell invasion.

Guo AK et al.

British Journal of Cancer, 2021

The carboxy-terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC-activation.

Dafinger C et al.

Journal of Cellular and Molecular Medicine, 2020

Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction.

Pal R et al.

Nature Communications, 2018

Activation of tyrosine kinases by mutation of the gatekeeper threonine.

Azam M et al.

Nature Structural & Molecular Biology, 2008

Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src.

Huveneers S et al.

Cancer Research, 2007

Sap-1/PTPRH activity is regulated by reversible dimerization.

Wälchli S et al.

Biochemical and Biophysical Research Communications, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."