Varaico: Literature-Extracted Genetic Variants

Gene:SRXN1
Variant:p.C99S
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SRXN1

NM_080725.3:p.C99S

Associated Papers

The desulfinylation enzyme sulfiredoxin-1 attenuates HSC activation and liver fibrosis by modulating the PTPN12-NLRP3 axis.

Kim JW et al.

Hepatology (baltimore, Md.), 2025

Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motility.

Bowers RR et al.

Biochemistry, 2012

Characterization of plant sulfiredoxin and role of sulphinic form of 2-Cys peroxiredoxin.

Iglesias-Baena I et al.

Journal of Experimental Botany, 2010

Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace.

Jönsson TJ et al.

Nature, 2008

A novel role for human sulfiredoxin in the reversal of glutathionylation.

Findlay VJ et al.

Cancer Research, 2006

Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.

Jönsson TJ et al.

Biochemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."