Varaico: Literature-Extracted Genetic Variants

Gene:STAP2
Variant:p.Y250F
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STAP2

NM_001013841.2:p.Y250F

Associated Papers

STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis.

Sekine Y et al.

Oncogene, 2012

STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation.

Ikeda O et al.

Biochemical and Biophysical Research Communications, 2009

Leukemia inhibitory factor-induced phosphorylation of STAP-2 on tyrosine-250 is involved in its STAT3-enhancing activity.

Sekine Y et al.

Biochemical and Biophysical Research Communications, 2007

STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif.

Minoguchi M et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."