Varaico: Literature-Extracted Genetic Variants

Gene:STAT1
Variant:p.T385A
Back to variants list

STAT1

NM_007315.4:p.T385A

Associated Papers

A novel interface between the N-terminal and coiled-coil domain of STAT1 functions in an auto-inhibitory manner.

Remling L et al.

Cell Communication and Signaling : Ccs, 2023

An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form.

Menon PR et al.

Cell Communication and Signaling : Ccs, 2022

STAT1 N-terminal domain discriminatively controls type I and type II IFN signaling.

Göder A et al.

Cytokine, 2021

The two interfaces of the STAT1 N-terminus exhibit opposite functions in IFNγ-regulated gene expression.

Staab J et al.

Molecular Immunology, 2015

Fatal combined immunodeficiency associated with heterozygous mutation in STAT1.

Sharfe N et al.

The Journal of Allergy and Clinical Immunology, 2014

A conserved motif in the linker domain of STAT1 transcription factor is required for both recognition and release from high-affinity DNA-binding sites.

Hüntelmann B et al.

Plos One, 2014

Clinically relevant dimer interface mutants of STAT1 transcription factor exhibit differential gene expression.

Staab J et al.

Plos One, 2013

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."