Varaico: Literature-Extracted Genetic Variants

Gene:STAT2
Variant:p.Y631F
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STAT2

NM_005419.4:p.Y631F

Associated Papers

TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity.

Mori R et al.

Scientific Reports, 2017

The role of signal transducer and activator of transcription-2 in the interferon response.

Steen HC et al.

Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research, 2012

A Mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis.

Scarzello AJ et al.

Molecular Biology of the Cell, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."