Varaico: Literature-Extracted Genetic Variants

Gene:STAT3
Variant:p.P715A
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STAT3

NM_139276.3:p.P715A

Associated Papers

Novel germline STAT3 gain-of-function mutation causes autoimmune diseases and severe growth failure.

Saito K et al.

The Journal of Allergy and Clinical Immunology. Global, 2024

Phospho-Ser727 triggers a multistep inactivation of STAT3 by rapid dissociation of pY705-SH2 through C-terminal tail modulation.

Yang J et al.

International Immunology, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."