Varaico: Literature-Extracted Genetic Variants

Gene:STAT3
Variant:p.K685Q
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STAT3

NM_139276.3:p.K685Q

Associated Papers

A-485 alleviates fibrosis and apoptosis in kidney by disrupting tandem activation of acetylation and phosphorylation on STAT3.

Du C et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2025

Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor.

Kang HJ et al.

Oncotarget, 2017

Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3.

Dasgupta M et al.

The Journal of Biological Chemistry, 2014

Structure, function, and regulation of STAT proteins.

Lim CP et al.

Molecular Biosystems, 2006

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

Wang R et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."