Associated Papers
Clinical relevance of mosaic variants detected by exome sequencing.
Ghosh R et al.
The Journal of Allergy and Clinical Immunology, 2026
Diagnostic criteria for NK cell large granular lymphocyte leukemia: validation through a multicentric international study.
Pastoret C et al.
Blood Advances, 2026
Multi-omic Study of Cutaneous T-Cell Lymphoma Reveals Single Cell Clonal Evolution in Progression and Therapy Resistance.
Dorando HK et al.
Blood, 2026
Targeted deep sequencing identifies mosaicism in patients with immune dysregulation.
Schmitz EG et al.
The Journal of Allergy and Clinical Immunology, 2026
Genomic determinants of response and resistance to pirtobrutinib in relapsed/refractory chronic lymphocytic leukemia.
Brown JR et al.
Blood, 2026
Divergent molecular pathways drive monomorphic epitheliotropic and enteropathy-associated intestinal T-cell lymphoma.
Vallois D et al.
Leukemia, 2026
STAT3 SH2 Domain Aspartic Acid 661 Mutations Activate Immune Gene Programs.
Lee HK et al.
Journal of Cellular and Molecular Medicine, 2026
Somatic mutation and selection at population scale.
Lawson ARJ et al.
Nature, 2025
Transcriptomic landscape of CD8+ and CD4 + T-LGL leukemia revealed the distinct impact of STAT3 and STAT5B activating mutations.
Calabretto G et al.
Leukemia, 2025
Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes.
Hiitola E et al.
Science Advances, 2025
Inborn errors of immunity underlie clonal T cell expansions in large granular lymphocyte leukemia.
Bravo-Perez C et al.
The Journal of Clinical Investigation, 2025
Efficacy and influencing factors of immunosuppressive therapy for pure red cell aplasia: meta-analysis and systematic review.
Yusup M et al.
Annals of Hematology, 2025
Clinical features and outcomes in large granular lymphocyte leukemia - associated pure red cell aplasia with STAT3 mutation.
Liu X et al.
Annals of Hematology, 2025
Mutational heterogeneities in STAT3 and clonal hematopoiesis-related genes in acquired pure red cell aplasia.
Kawakami T et al.
Annals of Hematology, 2025
Spotlight on amino acid changing mutations in the JAK-STAT pathway: from disease-specific mutation to general mutation databases.
Hoffmann M et al.
Scientific Reports, 2025
Single Cell Resolution Tracking of Cutaneous T-Cell Lymphoma Reveals Clonal Evolution in Disease Progression.
Dorando HK et al.
Biorxiv : the Preprint Server for Biology, 2025
T-cell Large Granular Lymphocytic Leukemia with a STAT3 Mutation Successfully Treated with Cord Blood Transplantation.
Tokunaga Y et al.
Internal Medicine (tokyo, Japan), 2025
Functional apoptosis profiling reveals vulnerabilities in T-cell large granular lymphocytic leukemia.
Shumilov E et al.
Annals of Hematology, 2025
Case Report: Medullary carcinoma of the pancreas with MLH1 promoter hypermethylation, induced deficient mismatch repair, successfully treated with an immune checkpoint inhibitor.
Ohtsubo K et al.
Frontiers in Oncology, 2025
HSP and CD279 gene expression as candidate biomarkers in symptomatic LGLL patients.
Talarico G et al.
Discover Oncology, 2024
Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations.
Myers CS et al.
Haematologica, 2024
Integrated Clinical Genotype-Phenotype Characteristics of STAT3-Mutated Myeloid Neoplasms.
Ye MT et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024
Investigation of the mutations in the genes involved in Janus kinase/signal transducer and activator of transcription pathway in canine large cell gastrointestinal lymphoma.
Tsuruta T et al.
The Journal of Veterinary Medical Science, 2024
Unidirectional association of clonal hematopoiesis with atherosclerosis development.
Díez-Díez M et al.
Nature Medicine, 2024
CCL22 mutations in large granular lymphocytic leukemia.
Mizuno Y et al.
Haematologica, 2024
Primary immune regulatory disorders (PIRD): expanding the mutation spectrum in Turkey and identification of sixteen novel variants.
Aykut A et al.
Immunologic Research, 2024
TP53 and KMT2D mutations associated with worse prognosis in peripheral T-cell lymphomas.
Wang L et al.
Cancer Medicine, 2024
Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.
Vanni I et al.
Journal of Translational Medicine, 2024
EBV+ nodal T/NK-cell lymphoma associated with clonal hematopoiesis and structural variations of the viral genome.
Kato S et al.
Blood Advances, 2024
Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics.
Cao B et al.
Bmc Medical Genomics, 2024
STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer.
D'Amico S et al.
Elife, 2024
Predictive and prognostic molecular biomarkers in lymphomas.
Iorgulescu JB et al.
Pathology, 2024
Mechanisms of action and resistance in histone methylation-targeted therapy.
Yamagishi M et al.
Nature, 2024
Pro-inflammatory cells sustain leukemic clonal expansion in T-cell large granular lymphocyte leukemia.
Vicenzetto C et al.
Haematologica, 2024
The highs and lows of cyclic thrombocytopenia.
Zhang H et al.
British Journal of Haematology, 2024
High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-driver mutations in severe COVID-19 patients.
Ronchini C et al.
Plos One, 2024
Gamma-delta T-cell large granular lymphocytic leukemia in the setting of rheumatologic diseases.
Gorodetskiy V et al.
Frontiers in Cell and Developmental Biology, 2024
Activating STAT3 mutations in CD8+ T-cells correlate to serological positivity in rheumatoid arthritis.
Moosic KB et al.
Frontiers in Immunology, 2024