Varaico: Literature-Extracted Genetic Variants

Gene:STAT3
Variant:p.D661N
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STAT3

NM_139276.3:p.D661N

Associated Papers

STAT3 SH2 Domain Aspartic Acid 661 Mutations Activate Immune Gene Programs.

Lee HK et al.

Journal of Cellular and Molecular Medicine, 2026

Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Kar SP et al.

Nature Genetics, 2022

35835912 (PubMed )
Supplement: 41588_2022_1121_MOESM3_ESM.xlsx › ST3

STAT3 mutations in "gray-zone" cases of T-cell large granular lymphocytic leukemia associated with autoimmune rheumatic diseases.

Gorodetskiy V et al.

Frontiers in Medicine, 2022

Analysis of a single-institution cohort of patients with Felty's syndrome and T-cell large granular lymphocytic leukemia in the setting of rheumatoid arthritis.

Gorodetskiy VR et al.

Rheumatology International, 2021

Simultaneous Presentation of Leukemic Non-Nodal Mantle Cell Lymphoma and Gamma-Delta T-Large Granular Lymphocytic Leukemia in a Patient with Rheumatoid Arthritis.

Gorodetskiy VR et al.

Cancer Management and Research, 2020

Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.

de Araujo ED et al.

Cancers, 2019

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Creixell P et al.

Cell, 2015

26388441 (PubMed )
Supplement: mmc9.xlsx › COSMIC_v67MappedToEnsembl_right
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."