Varaico: Literature-Extracted Genetic Variants

Gene:STAT3
Variant:p.M660R
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STAT3

NM_139276.3:p.M660R

Associated Papers

Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance.

Asano T et al.

The Journal of Experimental Medicine, 2021

Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.

de Araujo ED et al.

Cancers, 2019

A Novel STAT3 Mutation in a Qatari Patient With Hyper-IgE Syndrome.

Chaimowitz NS et al.

Frontiers in Pediatrics, 2019

Novel Mutation in SH2 Domain of STAT3 (p.M660T) in Hyper-IgE Syndrome with Sterno-Clavicular and Paravertebral Abscesses.

Saikia B et al.

Indian Journal of Pediatrics, 2017

The Ying and Yang of STAT3 in Human Disease.

Vogel TP et al.

Journal of Clinical Immunology, 2015

SH2-domain mutations in STAT3 in hyper-IgE syndrome patients result in impairment of IL-10 function.

Giacomelli M et al.

European Journal of Immunology, 2011

Uncovering an IL-10-dependent NF-kappaB recruitment to the IL-1ra promoter that is impaired in STAT3 functionally defective patients.

Tamassia N et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."