Associated Papers
Decreased IL-17-producing TH cells as a diagnostic marker for STAT signaling-related primary immunodeficiencies.
Molnár E et al.
The Journal of Allergy and Clinical Immunology. Global, 2026
STAT3-Dependent Regulation of CFTR and Ciliogenesis Is Essential for Mucociliary Clearance and Innate Airway Defense in Hyper-IgE Syndrome.
Sun L et al.
American Journal of Respiratory and Critical Care Medicine, 2025
Dysregulated Airway Host Defense in Hyper IgE Syndrome due to STAT3 Mutations.
Sun L et al.
Biorxiv : the Preprint Server for Biology, 2024
Novel STAT3 variant causing infantile-onset autoimmune disease.
Pan M et al.
Frontiers in Medicine, 2023
Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance.
Asano T et al.
The Journal of Experimental Medicine, 2021
Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.
de Araujo ED et al.
Cancers, 2019
A Novel STAT3 Mutation in a Qatari Patient With Hyper-IgE Syndrome.
Chaimowitz NS et al.
Frontiers in Pediatrics, 2019
Hyper IgE recurrent infection syndrome in South Asia: is there a different outcome?
de Silva R et al.
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology, 2018
Autoimmunity/inflammation in a monogenic primary immunodeficiency cohort.
Rae W et al.
Clinical & Translational Immunology, 2017
Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome.
Bocchini CE et al.
Blood, 2016
Distinct mutations at the same positions of STAT3 cause either loss or gain of function.
Chandrasekaran P et al.
The Journal of Allergy and Clinical Immunology, 2016
Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies.
Gao Y et al.
Plos One, 2016
Lung parenchyma surgery in autosomal dominant hyper-IgE syndrome.
Freeman AF et al.
Journal of Clinical Immunology, 2013
Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.
Saito M et al.
The Journal of Experimental Medicine, 2011