Varaico: Literature-Extracted Genetic Variants

Gene:STAT3
Variant:p.F408L
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STAT3

NM_139276.3:p.F408L

Associated Papers

Functional validation of a novel STAT3 'variant of unknown significance' identifies a new case of STAT3 GOF syndrome and reveals broad immune cell defects.

Mackie J et al.

Clinical and Experimental Immunology, 2025

Investigation of the mutations in the genes involved in Janus kinase/signal transducer and activator of transcription pathway in canine large cell gastrointestinal lymphoma.

Tsuruta T et al.

The Journal of Veterinary Medical Science, 2024

JAK inhibitors to treat STAT3 gain-of-function: a single-center report and literature review.

Atschekzei F et al.

Frontiers in Immunology, 2024

39247195 (PubMed )
Supplement: DataSheet1.pdf

Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.

Gao F et al.

Cancer Medicine, 2023

36971051 (PubMed )
Supplement: CAM4-12-10267-s001.xlsx › Sheet1

Genetic Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma: A Systemic Review and Association Analysis With Next-Generation Sequencing.

Gao F et al.

Frontiers in Genetics, 2021

34925435 (PubMed )
Supplement: DataSheet2.xlsx › Sheet1
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