Associated Papers
Decreased IL-17-producing TH cells as a diagnostic marker for STAT signaling-related primary immunodeficiencies.
Molnár E et al.
The Journal of Allergy and Clinical Immunology. Global, 2026
STAT3-Mutated Hyper-IgE Syndrome With Retroperitoneal Abscess in Adolescence.
Sugiyama H et al.
Clinical Case Reports, 2026
Job's not done: BCG-itis as the first manifestation of hyper-IgE syndrome. A case report and review of the literature.
Staines-Boone AT et al.
Clinical Immunology (orlando, Fla.), 2026
STAT3 regulates NK and NKT cell differentiation through C-X3-C motif chemokine receptor 1 (CX3CR1) in hyper-IgE syndrome.
Liu J et al.
Molecular Biomedicine, 2025
A Novel Hypomorphic STAT3 Gene Variant in a 7-year-old Male with Hyper-IgE Syndrome.
Higashigawa T et al.
Journal of Clinical Immunology, 2025
STAT3-Dependent Regulation of CFTR and Ciliogenesis Is Essential for Mucociliary Clearance and Innate Airway Defense in Hyper-IgE Syndrome.
Sun L et al.
American Journal of Respiratory and Critical Care Medicine, 2025
Clinical analysis of hyperimmunoglobulin E syndrome in children with STAT3 and DOCK8 mutations in different genotypes.
Xu CD et al.
Translational Pediatrics, 2025
Genetic Background of Eosinophilic Esophagitis and Esophageal Atresia in Children.
Ulkersoy I et al.
Digestive Diseases and Sciences, 2025
Pulmonary features and stage of disease in adult patients with hyper-IgE syndrome: a single-centre clinical study and literature review.
Xie T et al.
Orphanet Journal of Rare Diseases, 2025
Hyper IgE Syndromes: Understanding, Management, and Future Perspectives: A Narrative Review.
Salehi M et al.
Health Science Reports, 2025
Case Report: Biliary hemorrhage by intrahepatic pseudoaneurysm and asymptomatic right coronary artery pseudoaneurysm in a patient with STAT3 hyper IgE syndrome.
Fujita D et al.
Frontiers in Immunology, 2025
JAK/STAT in human diseases: a common axis in immunodeficiencies and hematological disorders.
Djidjik R et al.
Frontiers in Immunology, 2025
Neutrophil-avid nanocarrier uptake by STAT3 dominant-negative hyper-IgE syndrome patient neutrophils.
Rubey KM et al.
Life Science Alliance, 2024
Obstructive uropathy in STAT 3 hyper immunoglobulin E syndrome: A 5 year old Middle Eastern boy.
Bukhari EM et al.
Saudi Medical Journal, 2024
Long term longitudinal follow-up of an AD-HIES cohort: the impact of early diagnosis and enrollment to IPINet centers on the natural history of Job's syndrome.
Carrabba M et al.
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology, 2023
Primary Invasive Cutaneous Fusariosis in Patients with STAT3 Hyper-IgE Syndrome.
Abbara S et al.
Journal of Clinical Immunology, 2023
A challenging differential diagnosis in a patient with autosomal dominant STAT3 deficiency.
Bravo-Queipo-de-Llano B et al.
Pediatric Pulmonology, 2023
Multi-Omics Profiling in PGM3 and STAT3 Deficiencies: A Tale of Two Patients.
Jacob M et al.
International Journal of Molecular Sciences, 2023
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.
Flümann R et al.
Blood Cancer Discovery, 2023
Disseminated BCG Disease in a Patient with Hyper IgE Syndrome due to Dominant-Negative STAT3 Mutation-Case Report.
Urdinez L et al.
Journal of Clinical Immunology, 2023
Intraoral and maxillofacial abnormalities in patients with autosomal dominant hyper-IgE syndrome.
Tar I et al.
Central-european Journal of Immunology, 2023
C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency.
Xie X et al.
The Embo Journal, 2022
Malignancy in STAT3 Deficient Hyper IgE Syndrome.
Urban A et al.
Journal of Clinical Immunology, 2022
Omalizumab for STAT3 Hyper-IgE Syndromes in Adulthood: A Case Report and Literature Review.
Lan J et al.
Frontiers in Medicine, 2022
Global Expansion of Jeffrey's Insights: Jeffrey Modell Foundation's Genetic Sequencing Program for Primary Immunodeficiency.
Quinn J et al.
Frontiers in Immunology, 2022
Targeted Gene Sanger Sequencing Should Remain the First-Tier Genetic Test for Children Suspected to Have the Five Common X-Linked Inborn Errors of Immunity.
Chan KW et al.
Frontiers in Immunology, 2022
Dominant-negative signal transducer and activator of transcription (STAT)3 variants in adult patients: A single center experience.
Shamriz O et al.
Frontiers in Immunology, 2022
STAT3 is critical for skeletal development and bone homeostasis by regulating osteogenesis.
Zhou S et al.
Nature Communications, 2021
Genetic Analysis of a Cohort of 275 Patients with Hyper-IgE Syndromes and/or Chronic Mucocutaneous Candidiasis.
Frede N et al.
Journal of Clinical Immunology, 2021
Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance.
Asano T et al.
The Journal of Experimental Medicine, 2021
Rescue of STAT3 Function in Hyper-IgE Syndrome Using Adenine Base Editing.
Eberherr AC et al.
The Crispr Journal, 2021
Delayed diagnosis of hyperimmunoglobulin E syndrome with STAT3 mutation in mainland China: a case report and literature review.
Fang J et al.
The Journal of International Medical Research, 2021
Clinical Profile of Hyper-IgE Syndrome in India.
Saikia B et al.
Frontiers in Immunology, 2021
Defective Toll-Like Receptors Driven B Cell Response in Hyper IgE Syndrome Patients With STAT3 Mutations.
Gong R et al.
Frontiers in Pediatrics, 2021
Staphylococcus aureus and Hyper-IgE Syndrome.
Park B et al.
International Journal of Molecular Sciences, 2020
STAT3 modulates reprogramming efficiency of human somatic cells; insights from autosomal dominant Hyper IgE syndrome caused by STAT3 mutations.
Yu Z et al.
Biology Open, 2020
Retained primary teeth in STAT3 hyper-IgE syndrome: early intervention in childhood is essential.
Meixner I et al.
Orphanet Journal of Rare Diseases, 2020
Autosomal dominant hyper IgE syndrome from a single centre in Chongqing, China (2009-2018).
Xiang Q et al.
Scandinavian Journal of Immunology, 2020
Hematopoietic Stem Cell Transplantation and Vasculopathy Associated With STAT3-Dominant-Negative Hyper-IgE Syndrome.
Ponsford MJ et al.
Frontiers in Pediatrics, 2020
Impaired memory B-cell development and antibody maturation with a skewing toward IgE in patients with STAT3 hyper-IgE syndrome.
van de Veen W et al.
Allergy, 2019
Lung disease in STAT3 hyper-IgE syndrome requires intense therapy.
Kröner C et al.
Allergy, 2019
A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance.
Khourieh J et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019
The first cohort of Iranian patients with hyper immunoglobulin E syndrome: A long-term follow-up and genetic analysis.
Tavassoli M et al.
Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, 2019
Hyper IgE syndrome associated with novel and recurrent STAT3 mutations: Two case reports.
Deng Y et al.
Medicine, 2019
Unexpected relevant role of gene mosaicism in patients with primary immunodeficiency diseases.
Mensa-Vilaró A et al.
The Journal of Allergy and Clinical Immunology, 2019
A Novel STAT3 Mutation in a Qatari Patient With Hyper-IgE Syndrome.
Chaimowitz NS et al.
Frontiers in Pediatrics, 2019
The effects of signal transducer and activator of transcription three mutations on human platelets.
Aleva FE et al.
Platelets, 2018