Varaico: Literature-Extracted Genetic Variants

Gene:STAT5A
Variant:p.Y665H
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STAT5A

NM_001288718.2:p.Y665H

Associated Papers

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs.

Lee HK et al.

Life Science Alliance, 2025

40228864 (PubMed )
Supplement: LSA-2025-03222_TableS2.xlsx › overlapped_genes

Disease-Associated Mutations of the STAT5B SH2 Domain Regulate Cytokine-Driven Enhancer Function and Mammary Development.

Lee HK et al.

Journal of Mammary Gland Biology and Neoplasia, 2025

40163145 (PubMed )
Supplement: 10911_2025_9582_MOESM1_ESM.docx

Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.

de Araujo ED et al.

Cancers, 2019

STAT5BN642H is a driver mutation for T cell neoplasia.

Pham HTT et al.

The Journal of Clinical Investigation, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."