Associated Papers
STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs.
Lee HK et al.
Life Science Alliance, 2025
40228864 (PubMed )
Supplement: LSA-2025-03222_TableS2.xlsx › overlapped_genes
Disease-Associated Mutations of the STAT5B SH2 Domain Regulate Cytokine-Driven Enhancer Function and Mammary Development.
Lee HK et al.
Journal of Mammary Gland Biology and Neoplasia, 2025
Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia.
Bhattacharya D et al.
Blood Cancer Journal, 2022
Clinicopathological and molecular genomic features of monomorphic epitheliotropic intestinal T-cell lymphoma in the Chinese population: a study of 20 cases.
Chen C et al.
Diagnostic Pathology, 2021
JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL.
Wahnschaffe L et al.
Cancers, 2019
31766351 (PubMed )
Supplement: cancers-11-01833-s001.zip › supplementary_figures_and_tables_S5_and_S7.docx
STAT5BN642H is a driver mutation for T cell neoplasia.
Pham HTT et al.
The Journal of Clinical Investigation, 2018
High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia.
Andersson EI et al.
Blood, 2016
Mutations leading to constitutive active gp130/JAK1/STAT3 pathway.
Pilati C et al.
Cytokine & Growth Factor Reviews, 2015
How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5.
Langenfeld F et al.
Plos One, 2015
Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation.
Andersson EI et al.
Blood Cancer Journal, 2013
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia.
Rajala HL et al.
Blood, 2013
Transcription factor STAT5A is a substrate of Bruton's tyrosine kinase in B cells.
Mahajan S et al.
The Journal of Biological Chemistry, 2001
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