Associated Papers
Mosaic variants in KRAS and STAT5B associated with a mixed phenotype of 2 acquired errors of immunity.
Forkgen J et al.
The Journal of Allergy and Clinical Immunology, 2026
Disease-associated mutations in the STAT5B SH2 domain reprogram hepatic cholesterol and lipid metabolism.
Lee HK et al.
Biorxiv : the Preprint Server for Biology, 2025
Clinical Validation of a Rapid Automated Lymphoma Next-Generation Sequencing Panel.
Krigstein M et al.
Annals of Laboratory Medicine, 2025
Transcriptomic landscape of CD8+ and CD4 + T-LGL leukemia revealed the distinct impact of STAT3 and STAT5B activating mutations.
Calabretto G et al.
Leukemia, 2025
Y665F variant of mouse Stat5b protects against acute kidney injury through transcriptomic shifts in renal gene expression.
Jankowski J et al.
Scientific Reports, 2025
STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs.
Lee HK et al.
Life Science Alliance, 2025
Single-cell sequencing reveals shared clonal signatures in nonmalignant B and tumor cells in T-prolymphocytic leukemia.
Hesselager C et al.
Blood Neoplasia, 2025
Disease-Associated Mutations of the STAT5B SH2 Domain Regulate Cytokine-Driven Enhancer Function and Mammary Development.
Lee HK et al.
Journal of Mammary Gland Biology and Neoplasia, 2025
Y665F variant of mouse Stat5b protects against acute kidney injury through transcriptomic shifts in renal gene expression.
Jankowski J et al.
Biorxiv : the Preprint Server for Biology, 2025
T-cell Large Granular Lymphocytic Leukemia with a STAT3 Mutation Successfully Treated with Cord Blood Transplantation.
Tokunaga Y et al.
Internal Medicine (tokyo, Japan), 2025
The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain.
Haas-Neill L et al.
Protein Science : a Publication of the Protein Society, 2025
JAK/STAT in human diseases: a common axis in immunodeficiencies and hematological disorders.
Djidjik R et al.
Frontiers in Immunology, 2025
STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs.
Lee HK et al.
Biorxiv : the Preprint Server for Biology, 2024
CCL22 mutations in large granular lymphocytic leukemia.
Mizuno Y et al.
Haematologica, 2024
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging.
Jakobsen NA et al.
Cell Stem Cell, 2024
STAT5B mutations in myeloid neoplasms differ by disease subtypes but characterize a subset of chronic myeloid neoplasms with eosinophilia and/or basophilia.
Yin CC et al.
Haematologica, 2024
Involvement of the JAK-STAT pathway in the molecular landscape of tyrosine kinase fusion-negative hypereosinophilic syndromes: A nationwide CEREO study.
Groh M et al.
American Journal of Hematology, 2024
STAT5B SH2 variants disrupt mammary enhancers and the stability of genetic programs during pregnancy.
Lee HK et al.
Biorxiv : the Preprint Server for Biology, 2024
Predictive and prognostic molecular biomarkers in lymphomas.
Iorgulescu JB et al.
Pathology, 2024
Pro-inflammatory cells sustain leukemic clonal expansion in T-cell large granular lymphocyte leukemia.
Vicenzetto C et al.
Haematologica, 2024
Genomic landscape of T-large granular lymphocyte leukemia and chronic lymphoproliferative disorder of NK cells: a single institution experience.
Fei F et al.
Leukemia & Lymphoma, 2023
Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome.
Veloza L et al.
Haematologica, 2023
Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases.
Kim U et al.
International Journal of Molecular Sciences, 2022
Defining TCRγδ lymphoproliferative disorders by combined immunophenotypic and molecular evaluation.
Teramo A et al.
Nature Communications, 2022
Deregulation of JAK2 signaling underlies primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma.
Bastidas Torres AN et al.
Haematologica, 2022
Structural and mutational analysis of member-specific STAT functions.
Erdogan F et al.
Biochimica Et Biophysica Acta. General Subjects, 2022
Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia.
Bhattacharya D et al.
Blood Cancer Journal, 2022
STAT5b: A master regulator of key biological pathways.
Smith MR et al.
Frontiers in Immunology, 2022
Clinicopathological and molecular genomic features of monomorphic epitheliotropic intestinal T-cell lymphoma in the Chinese population: a study of 20 cases.
Chen C et al.
Diagnostic Pathology, 2021