Varaico: Literature-Extracted Genetic Variants

Gene:STAT6
Variant:p.V547A
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STAT6

NM_003153.5:p.V547A

Associated Papers

Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging.

Zhou Z et al.

Immunity, 2024

Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond.

Unknown Author

Trends in Immunology, 2024

Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion.

Xiong X et al.

International Journal of Molecular Sciences, 2022

Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity.

Xiong X et al.

Nature Communications, 2022

STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.

Onodera A et al.

The Journal of Experimental Medicine, 2010

Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma.

Ritz O et al.

Blood, 2009

Genomic structure, expression and characterization of a STAT5 homologue from pufferfish (Tetraodon fluviatilis).

Sung SC et al.

European Journal of Biochemistry, 2003

A gain-of-function mutation in STAT6.

Daniel C et al.

The Journal of Biological Chemistry, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."