Varaico: Literature-Extracted Genetic Variants

Gene:STIM1
Variant:p.D112A
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STIM1

NM_001382567.1:p.D112A

Associated Papers

Single-nucleotide polymorphisms in Orai1 associated with atopic dermatitis inhibit protein turnover, decrease calcium entry and disrupt calcium-dependent gene expression.

Yeh YC et al.

Human Molecular Genetics, 2020

Identification of key amino acid residues responsible for internal and external pH sensitivity of Orai1/STIM1 channels.

Tsujikawa H et al.

Scientific Reports, 2015

STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.

Gudlur A et al.

Nature Communications, 2014

The molecular physiology of CRAC channels.

Prakriya M

Immunological Reviews, 2009

Mechanistic view on domains mediating STIM1-Orai coupling.

Fahrner M et al.

Immunological Reviews, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."