Associated Papers
A single amino acid deletion in the ER Ca2+ sensor STIM1 reverses the in vitro and in vivo effects of the Stormorken syndrome-causing R304W mutation.
Gamage TH et al.
Science Signaling, 2023
Store-Operated Calcium Entry Mediated by ORAI and STIM.
Nguyen NT et al.
Comprehensive Physiology, 2018
Phosphorylation-mediated structural changes within the SOAR domain of stromal interaction molecule 1 enable specific activation of distinct Orai channels.
Thompson JL et al.
The Journal of Biological Chemistry, 2018
A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state.
Fahrner M et al.
Nature Communications, 2018
The STIM1: Orai Interaction.
Frischauf I et al.
Advances in Experimental Medicine and Biology, 2016
Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation.
Maus M et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015
Structural and functional mechanisms of CRAC channel regulation.
Shim AH et al.
Journal of Molecular Biology, 2015
STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry.
Stathopulos PB et al.
Nature Communications, 2013
24351972 (PubMed )
Supplement: ncomms3963-s1.pdf
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation.
Muik M et al.
The Embo Journal, 2011
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