Associated Papers
Comprehensive mutational characterization of the calcium-sensing STIM1 EF-hand reveals residues essential for structure and function.
Kamath ND et al.
Genetics, 2025
40737484 (PubMed )
Supplement: iyaf146_supplementary_data.zip › Supplementary_Table_4_GENETICS-2025-308212.xlsx › cBioPortal_241001
Comprehensive mutational characterization of the calcium-sensing STIM1 EF-hand reveals residues essential for structure and function.
Kamath ND et al.
Biorxiv : the Preprint Server for Biology, 2025
39896620 (PubMed )
Supplement: media-6.xlsx › cBioPortal_241001
Swing-out opening of stromal interaction molecule 1.
Horvath F et al.
Protein Science : a Publication of the Protein Society, 2023
Mapping interactions between the CRAC activation domain and CC1 regulating the activity of the ER Ca2+ sensor STIM1.
Shrestha N et al.
The Journal of Biological Chemistry, 2022
Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity.
Emrich SM et al.
The Journal of Biological Chemistry, 2019
A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state.
Fahrner M et al.
Nature Communications, 2018
Diseases caused by mutations in ORAI1 and STIM1.
Lacruz RS et al.
Annals of the New York Academy of Sciences, 2015
Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.
Ma G et al.
Nature Communications, 2015
26184105 (PubMed )
Supplement: ncomms8826-s1.pdf
A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).
Fahrner M et al.
The Journal of Biological Chemistry, 2014
STIM1 and SLC24A4 Are Critical for Enamel Maturation.
Wang S et al.
Journal of Dental Research, 2014
Initial activation of STIM1, the regulator of store-operated calcium entry.
Zhou Y et al.
Nature Structural & Molecular Biology, 2013
23851458 (PubMed )
Supplement: NIHMS483645-supplement-1.pdf
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation.
Muik M et al.
The Embo Journal, 2011
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