Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.R284M
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STING1

NM_198282.4:p.R284M

Associated Papers

Human Cytomegalovirus UL138 Protein Inhibits the STING Pathway and Reduces Interferon Beta mRNA Accumulation during Lytic and Latent Infections.

Albright ER et al.

Mbio, 2021

Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING.

Fang R et al.

Immunity, 2021

Association of homozygous variants of STING1 with outcome in human cervical cancer.

Lubbers JM et al.

Cancer Science, 2021

TMEM173 variants and potential importance to human biology and disease.

Patel S et al.

Genes and Immunity, 2019

Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production.

Konno H et al.

Oncogene, 2018

29367762 (PubMed )
Supplement: NIHMS928440-supplement-1.pdf

Disease-associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling.

Melki I et al.

The Journal of Allergy and Clinical Immunology, 2017

Regulating STING in health and disease.

Li Y et al.

Journal of Inflammation (london, England), 2017

cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.

Tao J et al.

Iubmb Life, 2016

Single amino acid change in STING leads to constitutive active signaling.

Tang ED et al.

Plos One, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."