Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.H232R
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STING1

NM_198282.4:p.H232R

Associated Papers

Germline Variants in the Immune Response-Related Genes: Possible Modifying Effect on Age-Dependent BRCA1 Penetrance in Breast Cancer Patient.

Kuligina ES et al.

Cancers, 2025

41374957 (PubMed )
Supplement: cancers-17-03756-s001.zip › Table_S4a.xlsx › Table_S4a

Association of TMEM173/STING1 Gene Variants with Severe COVID-19 Among Fully Vaccinated vs. Non-Vaccinated Individuals.

Vázquez-Coto D et al.

Life (basel, Switzerland), 2025

STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.

Zhu Z et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2023

Case report: Two unique nonsense mutations in HTRA1-related cerebral small vessel disease in a Chinese population and literature review.

Chen W et al.

Frontiers in Neurology, 2022

36619910 (PubMed )
Supplement: Data_Sheet_3.ZIP › case-C › 3.________ › CA2245B________.__________________________________.xlsx › sheet1

Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses.

Kennedy RB et al.

Frontiers in Immunology, 2020

STING modulators: Predictive significance in drug discovery.

Cui X et al.

European Journal of Medicinal Chemistry, 2019

Identification of HPV integration and gene mutation in HeLa cell line by integrated analysis of RNA-Seq and MS/MS data.

Sun H et al.

Journal of Proteome Research, 2015

25698088 (PubMed )
Supplement: pr500944c_si_009.xlsx › SNV

OASes and STING: adaptive evolution in concert.

Mozzi A et al.

Genome Biology and Evolution, 2015

The mechanism of double-stranded DNA sensing through the cGAS-STING pathway.

Shu C et al.

Cytokine & Growth Factor Reviews, 2014

Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA-microRNA regulatory network in nasopharyngeal carcinoma model systems.

Szeto CY et al.

Febs Open Bio, 2014

24490137 (PubMed )
Supplement: mmc5.xlsx › coding

Somatic signature of brain-specific single nucleotide variations in sporadic Alzheimer's disease.

Parcerisas A et al.

Journal of Alzheimer's Disease : Jad, 2014

25024348 (PubMed )
Supplement: sj-xls-6-alz-10.3233_jad-140891.xls › P8H

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.

Diner EJ et al.

Cell Reports, 2013

Identification and characterization of a loss-of-function human MPYS variant.

Jin L et al.

Genes and Immunity, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."