Associated Papers
Identification of a Novel Heterozygous Variant c.497g>a (p.gly166glu) in Exon 5 of the Sting1 Gene as the Causative Factor of Sting-Associated Vasculopathy With Onset in Infancy (SAVI): A Case Report.
Mansilla-Polo M et al.
Actas Dermo-sifiliograficas, 2025
STING: a multifaced player in cellular homeostasis.
Song K et al.
Human Molecular Genetics, 2025
Cell biological insights into human STING variants.
Koide S et al.
Cell Structure and Function, 2025
Mosaic TMEM173 gene mutation R284S leading to STING-associated vasculopathy with onset in infancy (SAVI).
Yang Z et al.
International Journal of Dermatology, 2025
Emerging concepts and treatments in autoinflammatory interferonopathies and monogenic systemic lupus erythematosus.
Goldbach-Mansky R et al.
Nature Reviews. Rheumatology, 2025
Decoding Missense Variants by Incorporating Phase Separation via Machine Learning.
Feng M et al.
Nature Communications, 2024
Membrane traffic governs the STING inflammatory signalling.
Taguchi T
Journal of Biochemistry, 2023
Case report: JAK1/2 inhibition with baricitinib in the treatment of STING-associated vasculopathy with onset in infancy.
Wu J et al.
Pediatric Rheumatology Online Journal, 2023
Monogenic lupus: Tracing the therapeutic implications from single gene mutations.
Jia X et al.
Clinical Immunology (orlando, Fla.), 2023
Treatment of STING-associated vasculopathy with onset in infancy in patients carrying a novel mutation in the TMEM173 gene with the JAK3-inhibitor tofacitinib.
Tokgun PE et al.
Archives of Rheumatology, 2023
Use of Tofacitinib for infant-onset STING-associated vasculopathy: A case report from China.
Shen D et al.
Medicine, 2022
Intracellular Sensing of DNA in Autoinflammation and Autoimmunity.
MacLauchlan S et al.
Arthritis & Rheumatology (hoboken, N.j.), 2022
MITA/STING-mediated antiviral immunity and autoimmunity: the evolution, mechanism, and intervention.
Zhong B et al.
Current Opinion in Immunology, 2022
Lung Inflammation in STING-Associated Vasculopathy with Onset in Infancy (SAVI).
David C et al.
Cells, 2022
The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.
Shindo R et al.
Frontiers in Cell and Developmental Biology, 2022
Molecular mechanisms of phenotypic variability in monogenic autoinflammatory diseases.
Aksentijevich I et al.
Nature Reviews. Rheumatology, 2021
STING inhibitors target the cyclic dinucleotide binding pocket.
Hong Z et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021
Stimulator of Interferon Genes-associated Vasculopathy with an Onset in Infancy Diagnosed after the Development of Atypical Pulmonary Lesions During Treatment as Juvenile Idiopathic Arthritis.
Nishida T et al.
Internal Medicine (tokyo, Japan), 2021
STING-Mediated Lung Inflammation and Beyond.
Frémond ML et al.
Journal of Clinical Immunology, 2021
The STING phase-separator suppresses innate immune signalling.
Yu X et al.
Nature Cell Biology, 2021
Case Report: Novel SAVI-Causing Variants in STING1 Expand the Clinical Disease Spectrum and Suggest a Refined Model of STING Activation.
Lin B et al.
Frontiers in Immunology, 2021
STING Signaling and Sterile Inflammation.
Couillin I et al.
Frontiers in Immunology, 2021
New Horizons in the Genetic Etiology of Systemic Lupus Erythematosus and Lupus-Like Disease: Monogenic Lupus and Beyond.
Demirkaya E et al.
Journal of Clinical Medicine, 2020
Familial Interstitial Lung Disease Caused by Mutation of the STING1 Gene.
Li J et al.
Frontiers in Pediatrics, 2020
Adult-Onset ANCA-Associated Vasculitis in SAVI: Extension of the Phenotypic Spectrum, Case Report and Review of the Literature.
Staels F et al.
Frontiers in Immunology, 2020
Stimulator of Interferon Genes-Associated Vasculopathy With Onset in Infancy: A Systematic Review of Case Reports.
Dai Y et al.
Frontiers in Pediatrics, 2020
STING modulators: Predictive significance in drug discovery.
Cui X et al.
European Journal of Medicinal Chemistry, 2019
Severe combined immunodeficiency in stimulator of interferon genes (STING) V154M/wild-type mice.
Bouis D et al.
The Journal of Allergy and Clinical Immunology, 2019
TMEM173 variants and potential importance to human biology and disease.
Patel S et al.
Genes and Immunity, 2019
Novel TMEM173 Mutation and the Role of Disease Modifying Alleles.
Keskitalo S et al.
Frontiers in Immunology, 2019
Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING.
Konno H et al.
Cell Reports, 2018
[Familial chilblain lupus : Type 1 interferonopathy with model character].
Fiehn C
Zeitschrift Fur Rheumatologie, 2017
Regulating STING in health and disease.
Li Y et al.
Journal of Inflammation (london, England), 2017
cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.
Tao J et al.
Iubmb Life, 2016