Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.E16G
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STK11

NM_000455.5:p.E16G

Associated Papers

Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer.

Lan T et al.

Nature Communications, 2024

38997257 (PubMed )
Supplement: 41467_2024_50157_MOESM6_ESM.xlsx › Sup_Fig.1a-MTHFD1_

Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms.

Lehtiö J et al.

Nature Cancer, 2021

34870237 (PubMed )
Supplement: EMS133264-supplement-Source_Data_to_Extended_Data_Fig_7.xlsx › Ex_Data_Fig7_e

A novel de novo mutation in LKB1 gene in a Chinese Peutz Jeghers syndrome patient significantly diminished p53 activity.

Liu L et al.

Clinics and Research in Hepatology and Gastroenterology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."