Associated Papers
A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cells.
Severino MB et al.
The Journal of Biological Chemistry, 2025
Somatic mutations in 3929 HPV positive cervical cells associated with infection outcome and HPV type.
Pinheiro M et al.
Nature Communications, 2024
cancercelllines.org-a novel resource for genomic variants in cancer cell lines.
Paloots R et al.
Database : the Journal of Biological Databases and Curation, 2024
Targeted next-generation sequencing of 491 lung cancers in clinical practice: Implications for future detection strategy and targeted therapy.
Liu XD et al.
Heliyon, 2024
Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel associations between genomic alterations, TMB, and PD-L1.
Wallen ZD et al.
Frontiers in Oncology, 2024
Molecular profiling and feasibility using a comprehensive hybrid capture panel on a consecutive series of non-small-cell lung cancer patients from a single centre.
Mosteiro M et al.
Esmo Open, 2023
Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma.
Dolgalev I et al.
Nature Communications, 2023
Phosphorylated nuclear DICER1 promotes open chromatin state and lineage plasticity of AT2 tumor cells in lung adenocarcinomas.
Reyes-Castro RA et al.
Science Advances, 2023
RB1 aberrations predict outcomes of immune checkpoint inhibitor combination therapy in NSCLC.
Wang Q et al.
Frontiers in Oncology, 2023
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors.
Lee JK et al.
Npj Precision Oncology, 2022
Targeted Next-Generation Sequencing-Based Multiple Gene Mutation Profiling of Patients with Rectal Adenocarcinoma Receiving or Not Receiving Neoadjuvant Chemoradiotherapy.
Chang YK et al.
International Journal of Molecular Sciences, 2022
Clinicopathologic Characteristics and Outcomes for Patients With KRAS G12D-Mutant NSCLC.
Cooper AJ et al.
Jto Clinical and Research Reports, 2022
Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.
Bartolacci C et al.
Nature Communications, 2022
Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA.
Finkle JD et al.
Npj Precision Oncology, 2021
Invasive Mucinous Adenocarcinomas With Spatially Separate Lung Lesions: Analysis of Clonal Relationship by Comparative Molecular Profiling.
Yang SR et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2021
Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component.
Suzuki M et al.
Translational Lung Cancer Research, 2021
LKB1 and cancer: The dual role of metabolic regulation.
Li TT et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2020
Characterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing.
Lang GT et al.
Nature Communications, 2020
Metachronous primary lung adenocarcinomas harboring distinct KRAS mutations.
Hu Y et al.
Thoracic Cancer, 2020
LKB1 Deficiency Renders NSCLC Cells Sensitive to ERK Inhibitors.
Caiola E et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2020
Activity of Birinapant, a SMAC Mimetic Compound, Alone or in Combination in NSCLCs With Different Mutations.
Colombo M et al.
Frontiers in Oncology, 2020
Overexpression and Selective Anticancer Efficacy of ENO3 in STK11 Mutant Lung Cancers.
Park C et al.
Molecules and Cells, 2019
Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma.
Winter H et al.
Cancers, 2019
Detection and verification of 2.3 million cancer mutations in NCI60 cancer cell lines with a cloud search engine.
Prakash A et al.
Journal of Proteomics, 2019
Targeted Gene Next-Generation Sequencing Panel in Patients with Advanced Lung Adenocarcinoma: Paving the Way for Clinical Implementation.
Fernandes MGO et al.
Cancers, 2019
STK11 gene analysis reveals a significant number of splice mutations in Chinese PJS patients.
Jiang YL et al.
Cancer Genetics, 2019
False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases.
Kim YH et al.
Plos One, 2019
PIK3CA mutation is a favorable prognostic factor in esophageal cancer: molecular profile by next-generation sequencing using surgically resected formalin-fixed, paraffin-embedded tissue.
Yokota T et al.
Bmc Cancer, 2018
Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.
Kim YS et al.
Bmc Urology, 2018
Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.
Lee JY et al.
Translational Oncology, 2018
Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Zhang H et al.
Nature Communications, 2017
Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer.
Pécuchet N et al.
Oncotarget, 2017
LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies.
Peña CG et al.
Advances in Experimental Medicine and Biology, 2017
Genomic heterogeneity of multiple synchronous lung cancer.
Liu Y et al.
Nature Communications, 2016
Hot spot mutations in Finnish non-small cell lung cancers.
Mäki-Nevala S et al.
Lung Cancer (amsterdam, Netherlands), 2016
Cardiac glycosides display selective efficacy for STK11 mutant lung cancer.
Kim N et al.
Scientific Reports, 2016
Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.
Lee JY et al.
Oncotarget, 2015
Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay.
Park K et al.
Oncotarget, 2015
CRKL oncogene is downregulated by p53 through miR-200s.
Tamura M et al.
Cancer Science, 2015
A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties.
Dahmani R et al.
Oncogene, 2015
Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas.
Tone AA et al.
Bmc Cancer, 2014
Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines.
Suzuki A et al.
Nucleic Acids Research, 2014
Bias from removing read duplication in ultra-deep sequencing experiments.
Zhou W et al.
Bioinformatics (oxford, England), 2014
High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.
Kim S et al.
Plos One, 2014
The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner.
Meng J et al.
Plos One, 2013
Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing.
Zang ZJ et al.
Cancer Research, 2011
Exome sequencing reveals comprehensive genomic alterations across eight cancer cell lines.
Chang H et al.
Plos One, 2011