Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.Y49D
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STK11

NM_000455.5:p.Y49D

Associated Papers

Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma.

Christodoulou E et al.

Pigment Cell & Melanoma Research, 2021

32767816 (PubMed )
Supplement: PCMR-34-122-s006.xlsx › Sheet1

STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.

Granado-Martínez P et al.

Communications Biology, 2020

Unraveling the Deleterious Effects of Cancer-Driven STK11 Mutants Through Conformational Sampling Approach.

Lopus M et al.

Cancer Informatics, 2016

Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery.

Hudson AM et al.

Cancer Research, 2014

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours.

Wong SQ et al.

Scientific Reports, 2013

Cutaneous melanoma susceptibility and progression genes.

de Snoo FA et al.

Cancer Letters, 2005

Mutations in the human LKB1/STK11 gene.

Launonen V

Human Mutation, 2005

LKB1, a protein kinase regulating cell proliferation and polarity.

Boudeau J et al.

Febs Letters, 2003

Somatic mutations in the Peutz-Jeghers (LKB1/STKII) gene in sporadic malignant melanomas.

Rowan A et al.

The Journal of Investigative Dermatology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."