Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.E165*
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STK11

NM_000455.5:p.E165*

Associated Papers

Comprehensive Evaluation of a 1021-Gene Panel in FFPE and Liquid Biopsy for Analytical and Clinical Use.

Meintani A et al.

International Journal of Molecular Sciences, 2025

40649709 (PubMed )
Supplement: ijms-26-05930-s001.zip › Supplementary_Table_2_and_Figure_S1.xlsx › Table_S3

Deciphering lung adenocarcinoma evolution and the role of LINE-1 retrotransposition.

Zhang T et al.

Biorxiv : the Preprint Server for Biology, 2025

40161734 (PubMed )
Supplement: media-2.xlsx › Supplementary_Table_4

Loss of the tumour suppressor LKB1/STK11 uncovers a leptin-mediated sensitivity mechanism to mitochondrial uncouplers for targeted cancer therapy.

Angelopoulou A et al.

Molecular Cancer, 2024

39048991 (PubMed )
Supplement: 12943_2024_2061_MOESM1_ESM.xlsx › LKB1-null_LUAD_AO__1

Clinical relevance of somatic mutations in Chinese lung adenocarcinoma and their prognostic implications for survival.

Li T et al.

Cancer Medicine, 2024

38770632 (PubMed )
Supplement: CAM4-13-e7227-s001.xlsx › Table_S2

Case report: Immunotherapy guided by molecular profiling of tumors: illustrative cases and literature review.

Ozdogan M et al.

Frontiers in Medicine, 2024

Clinical perspectives on the value of testing for STK11 and KEAP1 mutations in advanced NSCLC.

Shiller M et al.

Frontiers in Oncology, 2024

39703851 (PubMed )
Supplement: DataSheet2.xlsx › Supplemental_data

Serine/Threonine Kinase 11 Plays a Canonical Role in Malignant Progression of KRAS -Mutant and GNAS -Wild-Type Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Omori Y et al.

Annals of Surgery, 2023

Identification and Validation of Noncanonical RET Fusions in Non-Small-Cell Lung Cancer through DNA and RNA Sequencing.

Xiang C et al.

The Journal of Molecular Diagnostics : Jmd, 2022

CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.

Gutiontov SI et al.

Scientific Reports, 2021

34625620 (PubMed )
Supplement: 41598_2021_99524_MOESM2_ESM.xlsx › Mutations

Tumor Signature Analysis Implicates Hereditary Cancer Genes in Endometrial Cancer Development.

Kondrashova O et al.

Cancers, 2021

33917078 (PubMed )
Supplement: cancers-13-01762-s001.zip › Kondrashova_etal_Supp_Tables.xlsx › Table_S5

Pulmonary large cell neuroendocrine carcinoma with adenocarcinoma-like features: napsin A expression and genomic alterations.

Rekhtman N et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2018

Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer.

Pécuchet N et al.

Oncotarget, 2017

26625312 (PubMed )
Supplement: oncotarget-08-23831-s002.xls › Feuil1

Digital Sorting of Pure Cell Populations Enables Unambiguous Genetic Analysis of Heterogeneous Formalin-Fixed Paraffin-Embedded Tumors by Next Generation Sequencing.

Bolognesi C et al.

Scientific Reports, 2016

26864208 (PubMed )
Supplement: srep20944-s1.pdf

Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer.

Karlsson A et al.

Oncotarget, 2015

26124082 (PubMed )
Supplement: oncotarget-06-22028-s003.xlsx › Variants_in_Seidel

Tongue carcinoma infrequently harbor common actionable genetic alterations.

Tan DS et al.

Bmc Cancer, 2014

Multiplex genomic profiling of non-small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study.

Okamoto I et al.

Oncotarget, 2014

24810493 (PubMed )
Supplement: oncotarget-05-2293-s001.pdf

High Resolution Melting analysis as a rapid and efficient method of screening for small mutations in the STK11 gene in patients with Peutz-Jeghers syndrome.

Borun P et al.

Bmc Medical Genetics, 2013

Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.

Hearle N et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."