Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.I177N
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STK11

NM_000455.5:p.I177N

Associated Papers

Somatic STK11 mosaicism in a Turkish patient with Peutz-Jeghers syndrome.

Yilmaz M et al.

Familial Cancer, 2024

A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress.

Ritho J et al.

Cell Reports, 2015

Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC).

Kim DW et al.

Molecular Endocrinology (baltimore, Md.), 2007

Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome.

Mehenni H et al.

Digestive Diseases and Sciences, 2007

A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinoma.

Qiu W et al.

Oncogene, 2006

Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.

Boudeau J et al.

Human Mutation, 2003

Two novel mutations and a new STK11/LKB1 gene isoform in Peutz-Jeghers patients.

Resta N et al.

Human Mutation, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."