Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.L182P
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STK11

NM_000455.5:p.L182P

Associated Papers

LKB1 biology: assessing the therapeutic relevancy of LKB1 inhibitors.

Trelford CB et al.

Cell Communication and Signaling : Ccs, 2024

Effects of Peutz-Jeghers syndrome (PJS) causing missense mutations L67P, L182P, G242V and R297S on the structural dynamics of LKB1 (Liver kinase B1) protein.

Rungsung I et al.

Journal of Biomolecular Structure & Dynamics, 2019

Three novel mutations of STK11 gene in Chinese patients with Peutz-Jeghers syndrome.

Tan H et al.

Bmc Medical Genetics, 2016

NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas.

Meder L et al.

International Journal of Cancer, 2016

26340530 (PubMed )
Supplement: IJC-138-927-s005.xlsx › Tabelle1

A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress.

Ritho J et al.

Cell Reports, 2015

Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.

Hearle N et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2006

STK11 genotyping and cancer risk in Peutz-Jeghers syndrome.

Schumacher V et al.

Journal of Medical Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.

Schumacher V et al.

Human Genetics, 2005

Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.

Lim W et al.

British Journal of Cancer, 2003

LKB1, a protein kinase regulating cell proliferation and polarity.

Boudeau J et al.

Febs Letters, 2003

Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma.

Olschwang S et al.

Journal of Medical Genetics, 2001

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