Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.L282fs
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STK11

NM_000455.5:p.L282fs

Associated Papers

Co-occurrence of Peutz-Jeghers syndrome and unilateral multicystic dysplastic kidney: a case report.

Liu Y et al.

Bmc Nephrology, 2025

Unravelling the role of PLK1 in tumorigenesis by revealing the mutational landscape of colorectal and lung cancer with PLK1 mutations.

Wang S et al.

Journal of Cellular and Molecular Medicine, 2024

38887977 (PubMed )
Supplement: JCMM-28-e18497-s002.xlsx › Sheet1

Clinical perspectives on the value of testing for STK11 and KEAP1 mutations in advanced NSCLC.

Shiller M et al.

Frontiers in Oncology, 2024

39703851 (PubMed )
Supplement: DataSheet2.xlsx › Supplemental_data

Breaking the 'Undruggable' Barrier: Anti-PD-1/PD-L1 Immunotherapy for Non-Small Cell Lung Cancer Patients with KRAS Mutations-A Comprehensive Review and Description of Single Site Experience.

Chmielewska I et al.

Cancers, 2023

Detection and analysis of common pathogenic germline mutations in Peutz-Jeghers syndrome.

Gu GL et al.

World Journal of Gastroenterology, 2021

CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.

Gutiontov SI et al.

Scientific Reports, 2021

34625620 (PubMed )
Supplement: 41598_2021_99524_MOESM2_ESM.xlsx › Mutations

Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer.

Wohlhieter CA et al.

Cell Reports, 2020

33264619 (PubMed )
Supplement: NIHMS1651256-supplement-6.pdf

Clinical and Genetic Analyses of 38 Chinese Patients with Peutz-Jeghers Syndrome.

Wu BD et al.

Biomed Research International, 2020

32462036 (PubMed )
Supplement: 9159315.f1.zip › mat.9159315.v2.pdf

Relevance of STK11 Mutations Regarding Immune Cell Infiltration, Drug Sensitivity, and Cellular Processes in Lung Adenocarcinoma.

Li Z et al.

Frontiers in Oncology, 2020

Novel germline STK11 variants and breast cancer phenotype identified in an Indian cohort of Peutz-Jeghers syndrome.

Lipsa A et al.

Human Molecular Genetics, 2019

Impact of KRAS and TP53 Co-Mutations on Outcomes After First-Line Systemic Therapy Among Patients With STK11-Mutated Advanced Non-Small-Cell Lung Cancer.

Bange E et al.

Jco Precision Oncology, 2019

Two novel STK11 missense mutations induce phosphorylation of S6K and promote cell proliferation in Peutz-Jeghers syndrome.

Li R et al.

Oncology Letters, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."