Associated Papers
STK11 mutations and deletions define a distinct subtype of cervical adenocarcinoma.
Robinson E et al.
Medrxiv : the Preprint Server for Health Sciences, 2026
Genomic profiling in hepatocellular carcinoma: a real-world retrospective analysis.
Salani F et al.
Esmo Open, 2025
Multi-locus inherited neoplasia alleles syndromes in cancer: implications for clinical practice.
Yuen J et al.
European Journal of Human Genetics : Ejhg, 2025
Two missense STK11 gene variations impaired LKB1/adenosine monophosphate-activated protein kinase signaling in Peutz-Jeghers syndrome.
Liu J et al.
World Journal of Gastrointestinal Oncology, 2024
An atypical presentation of a pathogenic STK11 gene variant in siblings not fulfilling the clinical diagnostic criteria for Peutz-Jeghers Syndrome.
Shaunak M et al.
Journal of Pediatric Endocrinology & Metabolism : Jpem, 2022
Whole-Exome Sequencing Could Distinguish Primary Pulmonary Squamous Cell Carcinoma From Lung Metastases in Individuals With Cervical Squamous Cell Carcinoma.
Li L et al.
Pathology Oncology Research : Por, 2022
Actionable Molecular Alterations Are Revealed in Majority of Advanced Non-Small Cell Lung Cancer Patients by Genomic Tumor Profiling at Progression after First Line Treatment.
Frank MS et al.
Cancers, 2021
Comparative Analysis of Genetic Alterations, HPV-Status, and PD-L1 Expression in Neuroendocrine Carcinomas of the Cervix.
Takayanagi D et al.
Cancers, 2021
Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer.
Scholl SM et al.
Ebiomedicine, 2020
A step towards personalizing next line therapy for resected pancreatic and related cancer patients: A single institution's experience.
Lowder CY et al.
Surgical Oncology, 2020
Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.
Koyama T et al.
Bmc Cancer, 2019
STK11 gene analysis reveals a significant number of splice mutations in Chinese PJS patients.
Jiang YL et al.
Cancer Genetics, 2019
STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome.
Wang Z et al.
Human Mutation, 2014
Assessment of computational methods for predicting the effects of missense mutations in human cancers.
Gnad F et al.
Bmc Genomics, 2013
Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing.
Harismendy O et al.
Genome Biology, 2011
Truncating mutations in Peutz-Jeghers syndrome are associated with more polyps, surgical interventions and cancers.
Salloch H et al.
International Journal of Colorectal Disease, 2010
Somatic LKB1 mutations promote cervical cancer progression.
Wingo SN et al.
Plos One, 2009
Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC).
Kim DW et al.
Molecular Endocrinology (baltimore, Md.), 2007
Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome.
Mehenni H et al.
Digestive Diseases and Sciences, 2007
A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinoma.
Qiu W et al.
Oncogene, 2006
Exonic STK11 deletions are not a rare cause of Peutz-Jeghers syndrome.
Hearle NC et al.
Journal of Medical Genetics, 2006
High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome.
Aretz S et al.
Human Mutation, 2005
STK11 genotyping and cancer risk in Peutz-Jeghers syndrome.
Schumacher V et al.
Journal of Medical Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Schumacher V et al.
Human Genetics, 2005
Genotype-phenotype correlations in Peutz-Jeghers syndrome.
Amos CI et al.
Journal of Medical Genetics, 2004
Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.
Lim W et al.
British Journal of Cancer, 2003
LKB1, a protein kinase regulating cell proliferation and polarity.
Boudeau J et al.
Febs Letters, 2003
Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.
Boudeau J et al.
Human Mutation, 2003
Two novel mutations and a new STK11/LKB1 gene isoform in Peutz-Jeghers patients.
Resta N et al.
Human Mutation, 2002