Associated Papers
The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins.
Usher S et al.
Science Advances, 2025
Double mutation of open syntaxin and UNC-18 P334A leads to excitatory-inhibitory imbalance and impairs multiple aspects of C. elegans behavior.
Huang M et al.
Biorxiv : the Preprint Server for Biology, 2023
Munc18 - Munc13-dependent pathway of SNARE complex assembly is resistant to NSF and α-SNAP.
Xu Y et al.
The Febs Journal, 2022
SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex.
Stepien KP et al.
Science Advances, 2022
Exploring the Two Coupled Conformational Changes That Activate the Munc18-1/Syntaxin-1 Complex.
Gong J et al.
Frontiers in Molecular Neuroscience, 2021
Munc18-1 catalyzes neuronal SNARE assembly by templating SNARE association.
Jiao J et al.
Elife, 2018
Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.
Lai Y et al.
Neuron, 2017
Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Yue P et al.
Nature Communications, 2017
Conformational states of syntaxin-1 govern the necessity of N-peptide binding in exocytosis of PC12 cells and Caenorhabditis elegans.
Park S et al.
Molecular Biology of the Cell, 2016
Calcium-dependent activator protein for secretion 1 (CAPS1) binds to syntaxin-1 in a distinct mode from Munc13-1.
Parsaud L et al.
The Journal of Biological Chemistry, 2013
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex.
Ma C et al.
Nature Structural & Molecular Biology, 2011
Novel interactions of CAPS (Ca2+-dependent activator protein for secretion) with the three neuronal SNARE proteins required for vesicle fusion.
Daily NJ et al.
The Journal of Biological Chemistry, 2010
Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4.
Jewell JL et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 2010
Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans.
Johnson JR et al.
The Biochemical Journal, 2009
Activity determinants and functional specialization of Arabidopsis PEN1 syntaxin in innate immunity.
Pajonk S et al.
The Journal of Biological Chemistry, 2008
S-nitrosylation of syntaxin 1 at Cys(145) is a regulatory switch controlling Munc18-1 binding.
Palmer ZJ et al.
The Biochemical Journal, 2008
Munc18-1 prevents the formation of ectopic SNARE complexes in living cells.
Medine CN et al.
Journal of Cell Science, 2007
SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins.
Leung YM et al.
Endocrine Reviews, 2007
Interaction of Munc18 and Syntaxin in the regulation of insulin secretion.
Dong Y et al.
Biochemical and Biophysical Research Communications, 2007
Modulation of the K(v)4.3 channel by syntaxin 1A.
Ahmed I et al.
Biochemical and Biophysical Research Communications, 2007
Munc18c interaction with syntaxin 4 monomers and SNARE complex intermediates in GLUT4 vesicle trafficking.
D'Andrea-Merrins M et al.
The Journal of Biological Chemistry, 2007
Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes.
Zilly FE et al.
Plos Biology, 2006
Open form of syntaxin-1A is a more potent inhibitor than wild-type syntaxin-1A of Kv2.1 channels.
Leung YM et al.
The Biochemical Journal, 2005
Fluorescence resonance energy transfer reports properties of syntaxin1a interaction with Munc18-1 in vivo.
Liu J et al.
The Journal of Biological Chemistry, 2004
H3 domain of syntaxin 1A inhibits KATP channels by its actions on the sulfonylurea receptor 1 nucleotide-binding folds-1 and -2.
Cui N et al.
The Journal of Biological Chemistry, 2004
Syntaxin/Munc18 interactions in the late events during vesicle fusion and release in exocytosis.
Graham ME et al.
The Journal of Biological Chemistry, 2004
The Habc domain and the SNARE core complex are connected by a highly flexible linker.
Margittai M et al.
Biochemistry, 2003
Molecular determinants of syntaxin 1 modulation of N-type calcium channels.
Jarvis SE et al.
The Journal of Biological Chemistry, 2002