Varaico: Literature-Extracted Genetic Variants

Gene:SV2A
Variant:p.D670A
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SV2A

NM_014849.5:p.D670A

Associated Papers

Structural pharmacology of SV2A reveals an allosteric modulation mechanism in the major facilitator superfamily.

Pidathala S et al.

Nature Communications, 2025

41315229 (PubMed )
Supplement: 41467_2025_65781_MOESM4_ESM.xlsx › Figure_2B

Mechanisms underlying allosteric modulation of antiseizure medication binding to synaptic vesicle protein 2A (SV2A).

Mittal A et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants.

Mittal A et al.

Nature Structural & Molecular Biology, 2024

Further evidence for a differential interaction of brivaracetam and levetiracetam with the synaptic vesicle 2A protein.

Wood MD et al.

Epilepsia, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."