Varaico: Literature-Extracted Genetic Variants

Gene:SYK
Variant:p.Y348F
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SYK

NM_003177.7:p.Y348F

Associated Papers

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer.

Sadras T et al.

Molecular Cell, 2021

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells.

Lamb DJ et al.

Oncotarget, 2020

Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.

Hussain A et al.

The Journal of Biological Chemistry, 2013

Structural and biophysical characterization of the Syk activation switch.

Grädler U et al.

Journal of Molecular Biology, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."