Associated Papers
Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression.
Gagoski D et al.
Protein Science : a Publication of the Protein Society, 2025
41088778 (PubMed )
Supplement: PRO-34-e70317-s008.xlsx › _S6_-_PTMVar_-_Grb2
Novel SYK Variant Causes Enhanced SYK Autophosphorylation and PI3K Activation in an Antibody-Deficient Patient.
Edwards ESJ et al.
Journal of Clinical Immunology, 2025
Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression.
Gagoski D et al.
Biorxiv : the Preprint Server for Biology, 2025
39764007 (PubMed )
Supplement: media-1.xlsx › _S6_-_PTMVar_-_Grb2
Development of SYK NanoBRET Cellular Target Engagement Assays for Gain-of-Function Variants.
Capener JL et al.
Biorxiv : the Preprint Server for Biology, 2024
Gain-of-Function Variant in Spleen Tyrosine Kinase Regulates Macrophage Migration and Functions to Promote Intestinal Inflammation.
Yang Y et al.
Journal of Inflammation Research, 2024
Updates of cancer hallmarks in patients with inborn errors of immunity.
Wang Y et al.
Current Opinion in Allergy and Clinical Immunology, 2022
Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice.
Wang L et al.
Nature Genetics, 2021
Syk protein inhibitors treatment for the allergic symptoms associated with hyper immunoglobulin E syndromes: A focused on a computational approach.
Mansouri M et al.
International Journal of Immunopathology and Pharmacology, 0
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