Associated Papers
Structural basis and pathological implications of the dimeric OS9-SEL1L-HRD1 ERAD Core Complex.
Lin LL et al.
Nature Communications, 2026
Ubiquitination by HRD1 is essential for TLR3 trafficking and its innate immune signaling.
Zhao L et al.
Nature Communications, 2025
Structural basis and pathological implications of the dimeric OS9-SEL1L-HRD1 ERAD Core Complex.
Lin LL et al.
Biorxiv : the Preprint Server for Biology, 2025
Hypomorphic variants of SEL1L-HRD1 ER-associated degradation are associated with neurodevelopmental disorders.
Wang HH et al.
The Journal of Clinical Investigation, 2024
Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions.
Xu L et al.
Nature Cell Biology, 2020
Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.
Kim GH et al.
The Journal of Clinical Investigation, 2018
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