Associated Papers
Ubiquitination by HRD1 is essential for TLR3 trafficking and its innate immune signaling.
Zhao L et al.
Nature Communications, 2025
SLC35F2-SYVN1-TRIM59 axis critically regulates ferroptosis of pancreatic cancer cells by inhibiting endogenous p53.
Che B et al.
Oncogene, 2023
E3 ubiquitin ligase SYVN1 is a key positive regulator for GSDMD-mediated pyroptosis.
Shi Y et al.
Cell Death & Disease, 2022
Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.
Feng L et al.
Autophagy, 2017
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