Associated Papers
Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain.
Rizuan A et al.
Nature Communications, 2025
Repulsive vs Attractive Crowding Distinctly Regulate TDP-43 Condensates through Region-specific Structural Dynamics.
Zhang G et al.
Jacs Au, 2025
Pathological Mutations D169G and P112H Electrostatically Aggravate the Amyloidogenicity of the Functional Domain of TDP-43.
Pillai M et al.
Acs Chemical Neuroscience, 2024
Decoding Missense Variants by Incorporating Phase Separation via Machine Learning.
Feng M et al.
Nature Communications, 2024
39333476 (PubMed )
Supplement: 41467_2024_52580_MOESM4_ESM.xlsx › impact_ps_mutations
Structural details of helix-mediated TDP-43 C-terminal domain multimerization.
Rizuan A et al.
Biorxiv : the Preprint Server for Biology, 2024
Phosphomimetic substitutions in TDP-43's transiently α-helical region suppress phase separation.
Haider R et al.
Biophysical Journal, 2024
Dissecting the Effect of ALS Mutation G335D on the Early Aggregation of the TDP-43 Amyloidogenic Core Peptide: Helix-to-β-Sheet Transition and Conformational Shift.
Li F et al.
Journal of Chemical Information and Modeling, 2023
Role of Triggers on the Structural and Functional Facets of TAR DNA-binding Protein 43.
Camilus N et al.
Neuroscience, 2023
Atomistic Insights into A315E Mutation-Enhanced Pathogenicity of TDP-43 Core Fibrils.
Li F et al.
Acs Chemical Neuroscience, 2022
TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
Conicella AE et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020
Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing.
Kenna KP et al.
Journal of Medical Genetics, 2013
Select a paper to view details