Varaico: Literature-Extracted Genetic Variants

Gene:TARDBP
Variant:p.G146A
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TARDBP

NM_007375.4:p.G146A

Associated Papers

From TDP-43/RNA complex formation to disease-linked TDP-43 aggregation through a structural and cellular approach.

Feng Y et al.

Nature Communications, 2026

TDP-43 nuclear retention is antagonized by hypo-phosphorylation of its C-terminus in the cytoplasm.

Rabhi C et al.

Communications Biology, 2025

RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation.

Demongin C et al.

The Journal of Biological Chemistry, 2024

Role of Triggers on the Structural and Functional Facets of TAR DNA-binding Protein 43.

Camilus N et al.

Neuroscience, 2023

The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation.

Rengifo-Gonzalez JC et al.

Elife, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."