Varaico: Literature-Extracted Genetic Variants

Gene:TARDBP
Variant:p.D169A
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TARDBP

NM_007375.4:p.D169A

Associated Papers

TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2.

McGurk L et al.

Journal of Cell Science, 2020

32409565 (PubMed )
Supplement: joces-133-245811_review_history.pdf

The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.

Kuo PH et al.

Nucleic Acids Research, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."