Varaico: Literature-Extracted Genetic Variants

Gene:TARDBP
Variant:p.D169E
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TARDBP

NM_007375.4:p.D169E

Associated Papers

TDP-43 and ER Stress in Neurodegeneration: Friends or Foes?

de Mena L et al.

Frontiers in Molecular Neuroscience, 2021

The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity.

Li Q et al.

Nature Communications, 2015

TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage.

Suzuki H et al.

The Journal of Biological Chemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."